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5th Familial Cancer Conference

Not eligible for ESCO credits

07.06.2012  -  08.06.2012

Madrid, Spain

CONFERENCE

Medical / clinical oncology

Description

Chair: J. Benítez, ES - R. Eeles, UK - H. Vasen, NL


Dear Colleagues

It is our pleasure to welcome you again to the fifth Madrid Familial Cancer Conference that since 2004 we hold every two years. The present Conference, hosted at the Spanish National Cancer Research Centre (CNIO) aims to present recent advances in this field from a multidisciplinary point of view. During this decade, familial cancer has become an important challenge for oncologists, geneticists and molecular biologists, due to its implications not only at the individual but also at the familial and social level. This type of cancers affect several members of a single family, being the identification of high risk families, the knowledge of the genes responsible for specific diseases, the clinical follow up of mutation carriers, the development of new treatments and the discovery of tailored drugs, some of the different challenges involved. In most of European countries, the number of professionals working in this field has increased ten times over in the last years, demonstrating the interest that familial cancer has in our society. The Conference intends not only to cover and update numerous topics related to these genetic diseases but also to be a forum of discussion and meeting for professionals, either experienced clinicians and scientists or young people that are starting to work, or just interested in this exiting world.

Thank you all for coming to Madrid and we hope you enjoy a pleasant and successful Conference.

Javier Benitez, Hans Vasen, Rosalind Eeles


LEARNING OBJECTIVES
• To update recent advances in familial cancer
• To better define the genetic profile of these cancers and the clinical management of families and 
  patients.
• To analyze the impact of the new technologies and their contribution to familial cancer risk.


MAIN TOPICS
• General concepts in familial cancer: genetic variants, variants of unknown significance; modifier 
  factors; genetic counseling
• Common cancers: breast cancer and the family of breast cancer genes; selection criteria and 
  clinical management; new treatments; colorectal cancer and prostate cancer; genetic and
   clinical management.
• Other hereditary syndromes: Familial pheocromocitoma; pancreatic cancer; Birt-Hogg-Dube 
  syndrome; familial melanoma.
• Rare tumors: Fanconi anemia; Dysqueratosis congenital; genetic syndromes of the RAS/MAP 
  pathway; li Fraumeni syndrome.
• New technologies applied to familial cancer studies: Integrative genomic analysis; cancer 
  genome and personalized medicine; whole exome sequencing in the search of high 
  susceptibility genes.


The 4th Familial
Cancer
Conference is an
ESO-CNIO joint event

 

General information

ORGANISING SECRETARIAT
Carolina Garcia Sabaté
Centro Nacional de Investigaciones Oncológicas (CNIO) - Scientific Events Office
Melchor Fernández Almagro, 3
E-28029 Madrid - Spain
Tel: +34 91 224 6900
Fax: +34 91 224 6980
Email:
meetings@cnio.es


ESO SECRETARIAT
Daniela Mengato
European School of Oncology
Via del Bollo 4
20123 Milan - Italy
Tel: +39 02 8546 4523
Fax: +39 02 8546 4545
Email:
dmengato@eso.net



CONFERENCE
VENUE

Centro Nacional de InvestigacionesOncológicas (CNIO)
Melchor Fernández Almagro, 3
E-28029 Madrid - Spain


OFFICIAL LANGUAGE
The official language of the conference will be English. No simultaneous translation will be provided.


CERTIFICATES
All participants will be issued with a certificate of attendance at the close of the conference.


CME ACCREDITATION 
The European School of Oncology will apply for CME credits to the Accreditation Council of Oncology in Europe (ACOE). Information on the status of the application can be obtained from the organising secretariat.


BADGE
The badge is the only official evidence of registration and should be worn at all times during the conference. Loss of badge means loss of registration.


INSURANCE
The organisers bear no responsibility for untoward events in connection with, before, during and after the conference. Participants are strongly advised to take out their own personal and travel insurance coverage.


IMPORTANT DEADLINES
15/05/2012: poster abstracts deadline
15/05/2012: registration deadline (after this date, registration will only be available on-site)
15/05/2012: cancellation deadline
24/05/2012: replacement deadline

Faculty list


FACULTY
A. Antoniou, University of Cambridge, UK
J. Benítez, Centro Nacional de Investigaciones Oncológicas, Madrid, ES
G. Capellá, Instituto Catalan Oncologia, Barcelona, ES
A. Cascón, Centro Nacional de Investigaciones Oncológicas, Madrid, ES
A. Castells, Hospital Clínic, Barcelona, ES
F. Dantzer, University of Strasbourg, FR
R. Eeles, The Royal Marsden Hospital, Sutton, UK
D. Eccles, Southampton University Hospital Trust, UK
T. Frebourg, Rouen University Hospital, FR
M.J. García, Centro Nacional de Investigaciones Oncológicas, Madrid, ES
D. Goldgar, University of Utah, Salt Lake City, US
N. Gruis, Leiden University Medical Center, Leiden, NL
C. Guerra, Centro Nacional de Investigaciones Oncológicas, Madrid, ES
S. Hodgson, St. George's Hospital Medical School, London, UK
F. Menko, VU University Medical Center, Amsterdam, NL
R. Milne, Centro Nacional de Investigaciones Oncológicas, Madrid, ES
A. Osorio, Centro Nacional de Investigaciones Oncológicas, Madrid, ES
R. Perona, Instituto Investigaciones Biomedicas, Madrid, ES
J. Reis Filho, Institute Cancer Research, London, UK
M. Robledo, Centro Nacional de Investigaciones Oncológicas, Madrid, ES
D.H. Roukos, Ioannina University School of Medicine, Ioannina, GR
J. Surrallés, Universitat Autónoma de Barcelona, ES
M. Urioste, Centro Nacional de Investigaciones Oncológicas, Madrid, ES
H. Vasen, Leiden University Medical Centre, Leiden, NL

Programme

6 June

  19:30

WELCOME PARTY

 

7 June

 

GENERAL SESSION
Chair: J. Benítez, ES

  9:10

Hereditary cancer syndromes. Where do we go?  
J. Benítez, ES

  9:30

Genetic variants and familial cancer risk
R. Milne, ES 

  9:50Modifier  factors. Future applications
A. Antoniou, UK
 10:10

The problem of unknown variants
D. Goldgar, US

 10:30

Picture, posters, coffee break      

 11:10

Genetic counseling in familial cancer
S. Hodgson, UK 
 11:30Round table
 COMMON CANCERS I
Chair: S. Hodgson, UK 
 12:00

The family of breast cancer genes   
A. Osorio, ES 

 12:20Phenotype-genotype correlation in breast cancer 
J. Reis Filho, ES  
 12:40Pathological feature of endometrial cancer in Lynch syndrome 
J. Palacios, ES

 13:00

PARP inhibitors. Progress in cancer therapy   
F. Dantzer, FR   
 13:20Lunch break           

 14:45

Round table     

 15:15

Oral communications 
 15:55Coffee break
 16:30Clinical session
H. Vasen, NL - D. Eccles, UK

 

8 June

 

COMMON CANCERS II
Chair: F. Menko, NL      

  8:30

(Epi) genetics and clinical management of Lynch syndrome      
G. Capellá, ES     

  8:50

The genetics bases of FAP syndorme
B. Rivera, ES

  9:10Management of APC families including MUTYH families
A. Castells, ES
  9:30

Familial prostate cancer. Genetics and clinical management       
R. Eeles, UK

  9:50

Round table

 10:20

Coffee break

 

OTHER HEREDITARY CANCER SYNDROMES
Chair: R. Eeles, UK

 10:50

Genetic heterogeneity of Familial Pheocromocitoma            
M. Robledo, ES

 11:10

Pancreatic  cancer. Genetics and clinical management            
H. Vasen, NL 

 11:30Birt-hogg-Dube syndrome. Diagnosis and clinical management  
F. Menko, NL      
 11:50Clinical and genetic characteristics in familial malignant melanoma        
N. Gruis, NL    

 12:10

Round table       

 12:40

Oral communications
 13:00Lunch break    
 RARE TUMORS
M. Robledo, ES

 14:15

Fanconi Anemia                 
J. Surrallés, ES  

 14:35Dyskeratosis congenita               
R.Perona, ES
 14:55Genetic syndromes of the RAS/MAP pathway           
C. Guerra, ES

 15:15

LiFraumeni syndrome. From molecular bases to clinical management
T. Frebourg, FR

 15:35

Oral communication   

 15:45

Round table     

 16:15

Coffee break  
 NEW TECHNOLOGIES APPLIED TO FAMILIAL CANCER STUDIES
Chair: A. Osorio, ES 

 16:45

Identification of novel targets and regions through integrative genomic analysis    
M.J. García, ES

 17:05

The clinical potential of sequencing cancer genomes for personalized medicine
D.H. Roukos, GR  

 17:25

Whole exome sequencing in the search of high susceptibility genes     
A. Cascón, ES

 17:45

Oral communication  

 17:55

Round table  

Abstract



APPLICATION AND ABSTRACT SUBMISSION

You may apply and submit your abstract to the organising secretariat online at:
WWW.CNIO.ES/MEETINGS

Instructions for application and abstract submission
Participants with new data relevant to the subject of the conference may submit one abstract to be considered for poster presentation. Only papers whose abstracts have been reviewed and approved by the conference coordinators will be presented.
Abstracts should be written in English and the text should not exceed 3000 characters, title included.
The title should appear in capital letters.
For each author, type surname first, followed by first name and initials (presenting author in capital letters).
List of affiliations after the author's list.
Indicate 3-5 keywords at the end of the text.
The full address with telephone, fax number and email of the corresponding author must be provided. The corresponding author will receive all the subsequent communication concerning this abstract. Please also indicate your approval for publication in case the abstracts are issued
in a journal.
Eight abstracts will be selected for the oral presentation. We will notify it to the first author before May 15th.
It is the responsibility of the presenting author to ascertain whether all authors are aware of the content of the abstract before submission.


THE POSTER ABSTRACTS DEADLINE IS 15 MAY 2012