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2nd Masterclass on Systematic Reviews in Cancer Care, Guidelines and Research

30 ESCO credits

10.06.2016  -  14.06.2016

Belfast, United Kingdom

MASTERCLASS

Medical humanities

Description

 

Chairs: M. Clarke, UK - P. Johnston, UK


AIMS AND OBJECTIVES
This 5-day course will take participants through the key steps in preparing a systematic review of research in cancer that they can use to make decisions about treatment, guidelines or the design of new research. Each participant will bring a topic for a systematic review to the Masterclass, and this will form the basis of the problem-based learning approach that will be used throughout the course.

Each day of the Masterclass will include one or two formal lectures from experts in the relevant topic area, as well as group discussions relating to that topic area, drawing on the knowledge of the expert. The group discussions will be a mixture of whole-group work, and smaller discussions in which participants will be divided into small parallel groups to tackle specific issues relating to their review questions. These small groups will be facilitated by experienced systematic reviewers from the Faculty, and will conclude with a plenary session in which one member of each small group will provide feedback on specific issues that were discussed about the reviews in their group.


TEACHING FORMAT
Participants will bring a topic of their choosing to the Masterclass, and these topics will form the basis of the problem-based approach to learning that will be used throughout the course.  The course will be divided into eight sessions covering different aspects of the systematic review process. Each day will include one or two formal lectures from experts, as well as group discussions that draw on the knowledge of the expert. The group discussions will be a mixture of whole-group work and small-group work, in which participants will be divided into parallel groups to tackle specific issues relating to their review questions. These groups will be facilitated by experienced systematic reviewers from the Faculty, and will conclude with feedback presented by one member of each group.
Participants will be provided with a bibliography containing up to three key readings for each session. The Masterclass will be run entirely in English, and fluency is necessary for admission.


THE MASTERCLASS IS:

• A 5-day residential educational event
• Full immersion
• Clinically oriented
• Multidisciplinary


LEARNING OBJECTIVES
The Masterclass will help participants to strengthen the design of the review they are interested in and learn generic skills that they can apply to other systematic reviews. These skills will include the following key features for any systematic review:


• Formulation of the question
• Choice of inclusion and exclusion criteria, and selection of outcomes
• Development and implementation of a search strategy
• Application of the inclusion and exclusion criteria, and appraisal of quality and risk of bias in potentially eligible studies
• Data extraction
• Planning and conduct of meta-analyses, including subgroup and sensitivity analyses
• Exploration of heterogeneity
• Drawing conclusions and discussing implications for practice and research


MAIN TOPICS
• Question formulation for systematic reviews
• Eligibility criteria and outcome selection
• Search strategy
• Study quality and risk of bias
• Statistical analyses and heteorgeneity
• Implications for practice and research

       
       

 In collaboration with:

     
       

 Queen's University
Belfast

     
       

 The Cochrane
Collaboration

   
       
       

 Cochrane Methodology
Reviews

   
       
       

 

 

 

 

General information

ORGANISING SECRETARIAT    
European School of Oncology
Via Turati, 29
20121 Milan, Italy
Fax: +39 02 85464545
www.eso.net


Programme and Organisation
Francesca Marangoni
E-mail:
fmarangoni@eso.net

Ph: +39 02 85464525+39 02 85464525

Applications
Elena Fiore
E-mail:
efiore@eso.net

Ph: +39 02 85464529+39 02 85464529


ACCREDITATION
The event has been accredited by the European Accreditation Council for Continuing Medical Education (EACCME) to provide the following CME activity for medical specialists. The EACCME is an institution of the European Union of Medical Specialists (UEMS). The evaluation of the event has been performed by the Accreditation Council of Oncology in Europe (ACOE) that acknowledged the quality of the scientific programme and its educational value.
The event is designated for a maximum of 24 European CME credits (ECMEC).
Through an agreement between UEMS and the American Medical Association, physicians may convert EACCME credits to an equivalent number of AMA PRA Category 1 Credits™.



SOCIAL MEDIA
Tweet, network and follow updates using #16MSR on Twitter and Facebook.


 

Faculty list


FACULTY

F. Alderdice, Queen’s University Belfast, UK
C. Cardwell, Queen’s University Belfast, UK
M. Clarke, Queen’s University Belfast, UK
E. Gargon,  University of Liverpool, UK
S. Hopewell, University of Oxford, UK
P. Johnston, Queen’s University Belfast, UK
M. Lodge, International Network for Cancer Treatment and Research, Oxford, UK
L. Murray, Queen’s University Belfast, UK
S. Nolan, University of Liverpool, UK

Programme

 

10 June

     

12:00

 

Registration and lunch

13:00

  Welcome speech by Professor Patrick Johnston
Session 1: Formulating the question and eligibility criteria

 13:30

 

Lecture: What makes a good question for a systematic review
M. Clarke, UK

 

 

Group work: Each participant will outline the topic they have brought to the Masterclass and formulate the appropriate question that could be answered by a systematic review.

 15:00

  Coffee break

15:30

 

Lecture: Determining the inclusion and exclusion criteria for a systematic review
F. Alderdice, UK

 

 

Group work: Each participant will determine the inclusion and exclusion criteria for their systematic review.

17:30

  End of session
 19:30   Dinner
     

 

11 June

 

Session 2: Outcome selection

 9:00    

 

Lecture: The role of core outcome sets in systematic reviews 
E. Gargon, UK

 10:30

 

Coffee break

 11:00

 

Group work: Each participant will determine the inclusion and exclusion criteria for their systematic review.

 13:00

 

Lunch

Session 3: Search strategy

 14:00

  Lecture: How to develop a search strategy for a systematic review
M. Lodge, UK

 15:00

 

Coffee break

 15:30

 

Group work: Each participant will identify bibliographic databases and other sources of potentially eligible studies (e.g. prospective registries of clinical trials) that are likely to be high yield for their systematic review and explore the appropriate text words and index terms to use in a search of at least one of these databases.

 18:00

 

End of session

 19:30   Dinner
     

 

12 June

 

Session 4: Determining eligibility and data extraction

 9:00

 

Lecture: Developing a data extraction form and assessing the retrieved articles
M. Clarke, UK

 

 

Group work: Each participant will develop their plan for assessing the retrieved articles.

 10:30

 

Coffee break

 11:00

 

Group work: Each participant will prepare an outline for the data extraction form for their systematic review.

 13:00

 

Lunch

Session 5: Study quality and risk of bias
 14:00   Lecture: Assessing risk of bias in a systematic review
S. Hopewell, UK
 15:00  

Coffee break

 15:30   Group work: Each participant will consider the key areas of study quality and bias for their systematic review and the ways in which these might be assessed.
 18:00   End of session

19:30

  Dinner
     

 

13 June

 

Session 6: Statistical analyses (Part 1)

 9:00

 

Lecture: Meta-analysis of dichotomous and continuous data
M. Clarke, UK

 10:00

 

Coffee break

 10:30

  Group work: Each participant will develop a statistical analysis plan for their review, including the methods to be used to analyse the primary outcomes and any subgroup or sensitivity analyses.

 13:00

 

Lunch

Session 7: Statistical analyses (Part 2)

 14:00

 

Lecture: Meta-analysis of time to event data 
S. Nolan, UK

 

 

Group work: Each participant will continue to develop a statistical analysis plan for their review, including the methods to be used to investigate statistical.

15:30

  Coffee break

 16:00

 

Lecture: Meta-analysis of observational data
C. Cardwell, UK

 

  Group work: Each participant will consider how they might develop a statistical analysis plan for a review of epidemiological data.

 18:00

  End of session

 19:30

  Dinner
     

 

14 June

 

Session 8: Heterogeneity, strength and relevance of the evidence

  9:00

 

Lecture: Heterogeneity in systematic reviews 
L. Murray, UK

 9:30

 

Group work: Each participant will revisit the key sources of heterogeneity across the studies in their review, including those relating to the types of intervention or exposure, participant, outcome measures and study designs.

 10:30

 

Coffee break

 11:00

 

Lecture: What does your review mean for practice and research?  
M. Clarke, UK

 

 

Group work: Each participant will consider how they might communicate the findings of their review and influence decision making.

 13:00

 

Close of Masterclass and lunch