Centre Leon Berard

1. Training for the diagnosis and treatment of Sarcoma

Medical oncology, surgical oncology, radiotherapy & molecular oncology

Pr Jean-Yves BLAY & Prof Francois GOUIN

This  program is designated  as a training for the management of  adult soft tissue , visceral and  bone  sarcomas. It  is intended  for medical oncologist, radiotherapist, surcoma  surgical oncologist,  sarcoma  biopathologist and moecular  biologists.

It will provide a multidisciplinary  training, participation to  the  MDTs, and  to the work  ofof the NETSARC+ network adapted to the need  of the applicant depending on its specialty:

• Participation to the laboratory  and review work in the biopathology  department (Dr M. Karanian)
• Participation to the laboratory work of the team of  Dr F. Tirode, in the cancer  Research Center of 
• Participation to the outpatient clinic and surgery work of the  surgical department ( Pr F. Gouin)
• Participation to the outpatient clinic and medical oncology of the  surgical department ( Pr )

2. Training for the diagnosis and external radiotherapy treatment of H&N, pediatric, lung and SNC tumor; training in brachytherapy of cervix and prostate tumors.

Radiation oncology

Prof. V. Grégoire, Dr L. Claude, Dr R. Tanguy

• Clinical examination of patients including fiberoptic for H&N SCC
• Participation to the multidisciplinary tumor board
• Selection and delineation of organs at risk and target volumes
• Dose prescription
• Management of acute toxicities
• Possibilities of clinical research on files if long stay

3. Standard of management & New insights for Gynaecological cancers

Medical oncology, surgery, pathology, radiology, molecular oncology, fertility

Pr Isabelle Ray-Coquard  & / Drs Pierre Meeus -  N Chopin

• Training to key questions in surgery for Gyn Cancer
• Place of fertility surgery for patient with gyn cancer
• Pathology and expertise with second opinion for histology
• Dedicated program to rare Gyn tumors
• Place of medical oncology and systemic treatment for gyn cancer
• New drugs in Gyn Cancer
• Molecular oncology and targeted therapies i Gyn cancer
• Delineating clinical trials for GYn cancer

4. Management of Breast Imaging

Oncology Imaging  (Interventional, pathology , radiology)

Pr Frank PILLEUL / Dr Agnes COULON

• Educate in the advanced interpretation of mammography, breast ultrasound, breast MRI and in the accompanying image-guided biopsies.
• Educate in the epidemiology, diagnosis, pathology and therapy of breast cancer including screening for breast cancer and identification patterns of recurrence of malignant breast tumors.
• Provide an opportunity for participation in academic research.

5. Management of Interventional Oncology

Imaging Oncology, Interventional Imaging

Pr Frank Pilleul / Dr Amine Bouhamama

• Expose to all facets of the practice of Interventional Radiology, with emphasis on clinical evaluation and patient management.
• Training in clinical evaluation, non-procedural longitudinal patient management, peri-procedural care, and service/resource management.
• to provide training for fully integrated inpatient and outpatient capabilities including IR admissions and consult service.
• Vascular Interventions : Venous thrombolysis, stent deployment, IVC placement, Emergency Embolization.
• Oncologic Interventions: Chemoembolization, Radioembolization, Percutaneous Ablations (Radiofrequency, Microwave, and Cryo ablations), Percutaneous biopsies, Drain placements.

6. Diagnostic Imaging Program on Oncology disease

Radiology

Pr Frank Pilleul

• Educate trainees in the advanced interpretation of CT, MRI, and Ultrasound examination of the body and in the performance of ultrasound and CT guided procedures.
• Educate trainees in the biology, treatment and recurrence patterns of malignant tumors, particularly as they are reflected in body imaging studies. In addition, to educate trainees in the epidemiology, diagnosis, pathology and therapy of cancer, including screening and identification patterns of recurrence of malignant tumors.
• Provide an opportunity for academic research using the case material and resources of CL Bérard.

7. New drugs in hematological malignancies ( lymphoid malignancies, myelodysplasia and acute myeloid leukemia) and innovative  cellular therapy  ie CAR T cells malignacies

Hematology, cytapheresis, and cellular therapy

Dr Anne-Sophie MICHALLET- Dr Emmanuelle NICOLAS VIRELZIER- Dr Amine BELHABRI- Pr Mauricette MICHALLET

• Dedicated programs of new drugs in CLL and NHL
• Place of the new combination treatment using new drugs + chemotherpy in myelodysplasia and acute myeloid leukemia specifically in older population
• Developement of CAR T cells  in NHL, HD and CLL in clinical trials or in academic use
• Developement of CAR T cells in rare oncologic tumors
• Standard management of hematological malignancies ( NHL, HD, Myeloma, CLL, MDS)

8. Standard of management and new drugs in genito-urinary (GU) cancer ( germ cell tumor, prostate cancer: HSPC, mCRPC, CRPC M0, metastatic bladder cancer and perioperative treatment, renal cell carcinoma)

Medical Oncology

Dr Aude Fléchon- Dr Helen Boyle

• Standard management of GU cancer
• Training to key questions in the management of GU cancer
• Place of medical oncology and systemic treatment for GU cancer
• New drugs in GU Cancer
• Molecular oncology and targeted therapies in GU cancer
• Delineating clinical trials for GU cancer
• Place of the new combination treatment using new drugs + chemotherpy bladder cancer.

9. Training in thoracic oncology for the multidisciplinary management of non-small cell lung cancer, small cell lung cancer and rare thoracic tumours

Medical oncology

Dr Maurice Pérol, Dr Virginie Avrillon, Dr Aurélie Swalduz, Prof Pierre Saintigny (translational research), Dr Mayeul Tabutin (thoracic surgery), Dr Isabelle Martel-Lafay (radiotherapy)

Education in

• Mediastinal staging of lung cancer with EBUS
• Multidisciplinary management of early stages of NSCLC, including thoracic surgery and radiotherapy
• New treatments of advanced NSCLC including targeted therapies and immuno-oncology
• Management of SCLC, including new therapies
• Education to the management of rare thoracic tumours
• Management of patients in clinical trials
• Opportunity to participate into translational research

10. Training for the management of early breast cancer patients and therapeutic strategies based on molecular profiling for metastatic breast cancer patients

Medical & molecular oncology, surgery and radiation oncology

Drs Thomas Bachelot / Olivier Trédan / Isabelle Treilleux / Christelle Faure / Séverine Racadot

• Outpatient clinic rotation (diagnosis, breast surgery, chemotherapy, radiation oncology, endocrine treatment, follow-up)
• Participation to the multidisciplinary tumor boards (adjuvant setting and metastatic setting)
• Involved in the management of patients within clinical trials, especially in precision medicine
• opportunity to participate in the early drug development program
• opportunity to participate in the breast cancer translational research program