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BCY2 - 2nd Breast Cancer in Young Women Conference

9 ESCO credits

04.11.2014  -  05.11.2014

Dublin, Ireland


Breast cancer



F. Cardoso, PT -
B. Kaufman, IL - O. Pagani, CH - A.H. Partridge, US
Host Chair: J. Geraghty, IE
Conference Co-ordinator: S. Paluch-Shimon, IL

Breast cancer in young women is a devastating and complex disease. Breast cancer in women under 40 strikes when these women are at the peak of their reproductive years, family life and careers and still have many years ahead of them to suffer the long-term effects of treatment or the consequences of recurrent disease. The etiology of breast cancer in this population is poorly understood and most clinical trials focus on women who are over the age of 40, thus little evidence-based data is available about the optimal management of these patients. Further research is much needed in this field. This conference is an opportunity for the latest updates on this field and a platform for generating future research concepts and collaborations. It will cover epidemiology, molecular biology, genetics, pathology, surgery, radiotherapy, systemic therapy and fertility preservation in young women with breast cancer.

• In depth learning of various aspects of breast cancer in young women
• Importance of multi-disciplinary management
• Management of difficult clinical cases

• Hereditary breast cancer
• Diagnostic tools in young women
• Local therapy
• Systemic therapy
• Pregnancy and breast cancer
• Fertility preservation
• Psychosocial aspects
• Management of side effects
• Case discussions

• Medical oncologists
• Surgeons
• Gynaecologists
• Radiation oncologists
• Breast radiologists
• Onco-geneticists
• Pathologists
• Nurses
• Patient advocates

General information

European School of Oncology
Via Turati, 29 - 20121 Milan, Italy

Francesca Marangoni - fmarangoni@eso.net - Tel: +39 02 854645255
Roberta Ventura - rventura@eso.net - Tel: +39 02 854645322

Francesca Marangoni -
fmarangoni@eso.net - Tel: +39 02 854645255

O’Reilly Hall
University College Dublin
Belfield, Dublin 4
Map available here: www.ucd.ie/maps/UCD_Map_July_2011.pdf

O'Reilly Hall, the venue for BCY2 2014 is located in Belfield, the main University College Dublin campus, 4km south of Dublin city centre. UCD is directly accessible by bus, private car and taxi. O’Reilly Hall is located centrally on campus beside the lake. The most convenient vehicular and pedestrian access to this building is through the main gate in UCD via the N11. Enter through the main gate (N11) and turn right. Follow the road until you can see a large car park to your left, O’ Reilly Hall is overlooking this car park.  Please see the UCD map for exact location of O'Reilly Hall: www.ucd.ie/maps/UCD_Map_July_2011.pdf (N. 45, ref. C7).
Dublin International Airport Transport Links to UCD
Dublin is served by Dublin International Airport, which is located north of Dublin City Centre. Aircoach operates a service from Dublin Airport to Leopardstown / Sandyford / Stillorgan which passes UCD. Further details available at www.aircoach.ie/
Dublin Bus Links to UCD
Dublin Bus numbers 2, 3, 11, 17, 39A, 46A, 84 and 145 all provide services to the Belfield campus. The 39A terminates within the Belfield campus, and can be boarded from in the City Centre from College Street. The numbers 2, 3, 11 and 46A can be boarded at O'Connell Street. Several additional Xpresso services operate directly to campus during morning and evening peak. For timetable information please visit www.dublinbus.ie and search for University College Dublin.
Irish Rail Links to UCD
Dublin is served by two main railway stations: Connolly Station and Heuston Stations. It is a short walk from Connolly Station to O'Connell Street, where the Dublin Bus numbers 2, 11 and 46A can be boarded for UCD. The route 145 provides a direct route from Heuston Station to Belfield via the city centre. For further information please visit www.irishrail.ie
Regional Bus Links to UCD
Bus Éireann provides a nationwide bus service, with most major areas having a regular link to Dublin. The majority of Dublin services terminate in Busáras (Central Bus Station, Dublin) from where it is a short walk to O'Connell Street for connecting buses to UCD. Several Bus Éireann services from the Greater Dublin area directly serve UCD, Belfield Campus during morning peak. For further information please visit www.buseireann.ie

Taxis to UCD
There are usually an adequate number of taxis in operation in the city centre at any given time. It is possible to hail a taxi from the street, but convenient taxi ranks are located on O'Connell Street, Middle Abbey Street, Dame Street and St Stephens Green.


The official language will be English. No translation will be provided.

The organisers bear no responsibility for ontoward events in relation to the participation in the Conference. Participants are advised to take out their own personal and travel insurance coverage.

The abstract book has been published as a supplement to The Breast and will contain abstracts of the invited lecturers and those submitted by the participants that have been accepted for oral or poster presentation or for publication only. The three best abstracts have been selected and proposed for oral presentation.
The abstracts deadline was 30 June 2014.

Participants will be issued a certificate of attendance (details will be provided on the event-dedicated website).
The Accreditation Council of Oncology in Europe (ACOE) and the European Accreditation Council for Continuing Medical Education (EACCME) have acknowledged the quality of the scientific programme and its educational value. The Breast Cancer in Young Women Conference (BCY2) has been assigned 9 European Continuing Medical Education Credits (ECMEC).
Through an agreement between the European Union of Medical Specialists and the American Medical Association, physicians may convert EACCME credits to an equivalent number of AMA PRA Category 1 Credits™.
Information on the process to convert EACCME credit to AMA credit can be found at www.amaassn.org/go/internationalcme. EACCME certificate will be recognised by the Irish Postgraduate Training Bodies and Irish participants will be entitled to record these credits for purposes of Continuing Professional Development (CDP).
The programme was furthermore awarded with 10 cat. 1 ESMO-MORA points.

ESO is grateful to The Breast Cancer Research Foundation, Susan G. Komen for having provided travel grants to support the participation of:

Farah Arshad (India), Ivana Bozovic (Serbia), Allen Braude (Canada), Linda Dias (Canada), Mirza Gafur-Akhunova Kamola (Uzbekistan), Swanna Ginsberg (Canada), Arin Hanson (US), Galina Kuznecova (Latvia), Sergej Kuznecovs (Latvia), Matteo Lambertini (US), Tamta Makharadze (Georgia), Maqsud Mallayev (Uzbekistan), Megan McCann (US), Joshua Ngwang Menang (Cameroon), Jennifer Merschdorf (US), Agnes Musonda (Zambia), Amanda Nixon (US), Katherine Petrides (US), Shankpal Pramod (India), Shoshana Rosenberg (US), Jane Rowe (US), Charu Singh (India), Elizabeth Vella (Malta), Desiree Walker (US), Jessica Weller (UK)

Free Wi-Fi internet access in all areas of the BCY2 venue is available.

Please note that capturing contents of the sessions is prohibited.

Tuesday, 4 November  11:00-19:30
Wednesday, 5 November 8:00-17.45

Tuesday, 4 November  13:30-19:30
Wednesday, 5 November 9:00-17:45

Members of the faculty are invited to refer to the Speakers Room.

A valid passport and/or identity card is required for entry into Dublin. A visa may be required for some countries. For specific information, please visit the department of Foreign affairs and Trade website at www.dfa.ie.

Late registration: 12 October 2014
On-site registration: after 12 October 2014



Consensus recommendations for management of breast cancer in young women were developed after the 1st International Consensus Conference for Breast Cancer in Young Women (BCY1) and areas of research priorities were identified. It’s been published a manuscript that summarizes these international consensus recommendations, which are also endorsed by the European Society of Breast Specialists (EUSOMA).
First international consensus guidelines for breast cancer in young women (BCY1)
Ann H. Patridge, Olivia Pagani, Omalkhair Abulkhair, Federic Amant, Hatem A. Azim Jr, Alberto Costa, Suzette Delaloge, Gloria Freilich, Oreste Davide Gentilini, Nadia Harbeck, Catherine M. Kelly, Sibylle Loibl, Dror Meirow, Fedro Peccatori, Bella Kaufmann, Fatima Cardoso
The Breast, volume 23, issue 3, pages 209 – 220, June 2014
To view the consensus guidelines, please click here.


Faculty list


F. Cardoso, Champalimaud Cancer Center, Lisbon, PT
J. Geraghty, St. Vincent Hospital, Dublin, Ireland

B. Kaufman, Sheba Medical Center, Tel Hashomer, IL
O. Pagani
, Oncology Institute of Southern Switzerland (IOSI), Bellinzona, CH
A.H. Partridge, Dana-Farber Cancer Institute, Boston, US

J. Armstrong, St. Luke's Hospital, Dublin, IE
N. Elmer
, Dublin, IE
E. Evron
, Assaf Hospital, Zerifin, IL
L. Fallowfield, Brighton & Sussex Medical School, Brighton, UK
D. Fenlon, University of Southampton, Southampton, UK
E. Friedman
, Sheba Medical Center, Tel Hashomer, IL
J. Garber, Dana Farber Cancer Institute, Boston, US
K. Gelmon, BC Cancer Agency, Vancouver, CA
O. Gentilini, European Institute of Oncology, Milan, IT
A. Green
, Our Lady’s Hospital, Dublin, IE
N. Harbeck
, Hospital of the University of Munich (LMU), Munich, DE
S. Higgins, Adelaide and Meath Hospital, Dublin, IE
I. Kadmon
, Henrietta Szold Hadassah and the Hebrew University School of Nursing, Jerusalem, IL
E. Levy Lahad
, Shaare Zedek Medical Center, Jerusalem, IL
S. Loibl, German Breast Group, GBG Forschungs GmbH, Neu-Isenburg, DE
E. Bar-Meir, Plastic Surgeon, Haifa, IL
E.C. Moser, Champalimaud Foundation, Lisbon, PT
S. Paluch-Shimon, Sheba Medical Center, Ramat Gan, IL
F.A. Peccatori, European Institute of Oncology, Milano, IT
H. Raanani, Sheba Medical Center, Ramat Gan, IL
M. Sklair-Levy, Sheba Medical Center, Tel Hashomer, IL
M. Ziv, Israel Cancer Association, Givatayim, IL



4 November

Chairs: B. Kaufman, IL - F. Cardoso, PT

13:30 Welcome (B. Kaufman, IL)
13:40 Presentation by Israel Cancer Association (M. Ziv, IL) [Abs IN1]
13:50 KEYNOTE 1: Presentation by young patient (N. Elmer, IE)
14:05 KEYNOTE 2: Breast cancer in young women:        A rare disease or a significant public health problem?         (A.H. Partridge, US) [Abs IN2]

 14:20 SESSION 1: Diagnostic tools
Chair: J. Garber, US
  14:20 Controversies in breast cancer screening and diagnosis in young         women (M. Sklair-Levy, IL)
14:35 New technologies in breast imaging (M. Sklair-Levy, IL) [Abs IN3]
14:50 Discussion
 15:00 Coffee break
 15:30  SESSION 2: Familial and hereditary breast cancer
Chairs: S. Paluch-Shimon, IL - A. Green, IE
  15:30 Genetic testing in young patient - what is the right time? (E. Levy-Lahad, IL)
15:50 High risk families without founder BRCA1/2 mutations (E. Friedman, IL)
16:10 Local therapy considerations in BRCA1/2 mutations
carriers with breast cancer (E. Evron, IL) [Abs IN4]
16:30 Systemic therapies in BRCA+ breast cancer - what's new? (J. Garber, US)
16:50 Discussion
 17:00 SESSION 3: Loco-regional therapy 
Chairs: J. Geraghty, IE - J. Armstrong, IE
  17:00 Mastectomy or breast conserving surgery for young women with         breast cancer (O. Gentilini, IT)
17:15 Breast reconstruction - immediate vs delayed? (E. Bar Meir, IL)
17:30 Considerations in radiotherapy for young women - age, stage and         biology (E.C. Moser, PT) [Abs IN5]
17:45 Discussion


 NURSING SESSION (Session held in collaboration with EONS)
Chair: I. Kadmon, IL
18:00 Keynote lecture: Nursing younger women with breast cancer [Abs IN6]
D. Fenlon, UK

5 November

 9:00 SESSION 4: Tumour biology
Chair: F. Cardoso, PT

  09:00 Age and tumor biology (K. Gelmon, CA) [Abs IN7]
 9:20 SESSION 5: Systemic therapies
Chairs: A.H. Partridge, US - K. Gelmon, CA 

09:20 The role of neo-adjuvant therapy in young women (S. Loibl, DE) [Abs IN8]
09:35 The management of triple negative breast cancer (N. Harbeck, DE)
[Abs IN9]
09:50 What's new in endocrine therapy in young women (O. Pagani, CH)
[Abs IN10]
10:05 Do we need clinical trials that target young women with breast cancer? (B. Kaufman, IL)
10:20 Discussion

 10:30 Coffee break
 11:00 SESSION 6: Fertility and pregnancy
Chairs: S. Loibl, DE - F.A. Peccatori, IT
  11:00 Pregnancy after breast cancer (S. Paluch-Shimon, IL)
11:15 Updates in fertility preservation (H. Raanani, IL)
11:30 Discussion
 11:40 Case Discussion - early breast cancer
Chairs: A. Partridge, US - B. Kaufman, IL
 12:10 Best abstracts presentation
Chairs: B. Kaufman, IL
- PGD decisions among young Israeli BRCA1/2 mutation carriers
(E. Dagan, IL) [Abs OR15] 
- Prospective study of fertility preservation strategies in young early breast cancer patients (pts): the PREFER (PREgnancy and FERtility) trial
(M. Lambertini, US) [Abs OR30]  
- Meeting the diverse but unique needs of young women diagnosed with breast cancer: a toolkit   approach
(M. McCann, US) [Abs OR68]

 12:40 Lunch and poster session



SESSION 7: Advanced breast bancer
Chair: B. Kaufman, IL

  Do we know how to treat ABC in young women? (F. Cardoso, PT)


 Case Discussion - advanced breast cancer
Chairs: F. Cardoso, PT - S. Paluch-Shimon, IL


 SESSION 8: Survivorship and quality of life issues
Chairs: N. Harbeck, DE - O. Pagani, CH


 14:30 "Oncobrain" - is it real and what can be done? (A. Partridge, US) [Abs IN11]
14:45 Survivorship issues (F.A. Peccatori, IT)
15:00 Psycho-oncology issues (L. Fallowfield, UK)
15:15 Issues in palliative care in young patients (S. Higgins, IE)
15:30 Discussion



Coffee break

 16:10 SESSION 9:
Breast Cancer in Young Women Conference Statement
F. Cardoso, PT - B. Kaufman, IL - L. Fallowfield, UK - D. Fenlon, UK - K. Gelmon, CA - J. Geraghty, IE - N. Harbeck, DE - S. Higgins, IE - S. Loibl, DE - E. Moser, PT - O. Pagani, CH - S. Paluch-Shimon, IL - A.H. Partridge, US - F.A. Peccatori, IT - H. Raanani, IL




  A prefix has been added to the abstract number to identify the type of presentation or acceptance:
IN: Abstracts submitted by invited speakers
OR: Abstracts accepted for oral presentation
HM: Abstracts awarded Honorable Mention
PO: Abstracts accepted for poster presentation



OR15 PGD decisions among young Israeli BRCA1/2 mutation carriers. Efrat Dagan, IL
PO16 Lipid Profiling of Benign atypical and malignant Breast Cancer tissues in Indian females by 1 H NMR spectroscopy: analyzing its utility as diagnostic aid in early malignancy detection. Farah Arshad, IN
PO17 Role of BRCA - 1 gene in development of breast cancer. Kamola Gafur-Akhunova, UZ
PO18 BRCA1/BRCA2(BRCA) testing in young women with breast cancer: patterns, motivations and implications for treatment decisions. Shoshana Rosenberg, US
OR30 Prospective study of fertility preservation strategies in young early breast cancer patients (pts): the PREFER (PREgnancy and FERtility) trial. Matteo Lambertini, IT
HM31 Breast cancer in young women? Age a risk factor only in those not given chemotherapy. Hanna Fredholm, SE
HM32 Cognitive coping in young women with breast cancer. Rameet Sachdev, US
PO33 Clinical practice guideline for preservation of fertility in breast cancer patients in Japan. Hiroko Bando, JP
PO34 Clinico-pathologic features of young breast cancer patients treated at the Institute for Oncology and Radiology of Serbia. Ivana Bozovic-Spasojevic, RS
PO35 What do women want? Fertility preservation preferences of young Israeli breast cancer patients. Efrat Dagan, IL
PO36 Clinicopathologic characteristics of breast cancer in young women:  Croatian single institution experience. Natalija Dedić Plavetić, HR
PO37 Hpr: a randomized chemoprevention trial in high risk women. Irene Feroce, IT
PO38 An analysis of breast cancer incidence in young women: a single site study. Tamta Makharadze, GE
PO39 Breast cancer in young women in Uzbekistan. Maksud Mallaev, UZ
PO40 Reproductive Health Decisions Following Breast Cancer Diagnosis. Courtney Preusse, US
PO42 Effect of gonadotropin releasing hormone (GnRH ) agonist on menstrual reverse in young breast cancer cases treated with cyclophosphamide. Charu Singh, IN
PO43 Fertility concerns and in young breast cancer patients. Charu Singh, IN
PO44 Obesity does not Influence the Character of the Breast Cancer in Premenopause Women. Masahiko Suzuki, JP
PO45 Clinicopathological evaluation and outcome of young breast cancer patients developing brain metastasis in single institution cohort. Malgorzata Tuxen, DK
PO46 Unmet needs and biographic changes among young breast cancer survivors. Rachel Wuerstlein, DE
PO47 Breast cancer in young woman during pregnancy and lactation. Lola Zakirova, UZ
PO48 Pregnancy-associated breast cancer (PABC): Czech Young Breast Cancer Study Group Project 35. Martina Zimovjanova, CZ
OR68 Meeting the diverse but unique needs of young women diagnosed with breast cancer: a toolkit approach. Megan McCann, US
PO69 Breast cancer in young women in Canada? A needs assessment. Shawna Ginsberg, CA
PO70 About Her - Building community and creating dialogue through story telling and film. Shawna Ginsberg, CA
PO71 Breast Cancer in the Family - Helping Children Cope. Shawna Ginsberg, CA
PO72 Using a national needs assessment to direct programs for young women affected by breast cancer in the United States. Arin Hanson, US
PO73 Communication with young women with breast cancer. Labrini Kourkouta, GR
PO74 Knowledge about lymphedema, risk perception and primary prevention in breast cancer patients. Galina Kuznecova, LV
PO75 Connecting young women:  face to face support networks. Megan McCann, US
PO76 Breast cancer and cultural practices. Ngwang Menang, CM
PO77 Evaluation of young Breast-cancer sufferers survival: novel initiative by Indian cancer  NGO. S. Pramod, IN
PO78 Diagnosis of Breast cancer on young couples: strategies  in facing terminal illness. S. Pramod, IN
PO79 Sensitizing  Primary healthcare workers towards psychosocial issues in young breast-cancer women: policy paper for NGOs in developing nations. S. Pramod, IN
PO81 Survivorlink: evolution of 1:1 peer support to connect young women with breast cancer. Jean Rowe, US
PO82 Surveying young women with metastatic breast cancer (YWMBC) to create interventions with impact. Jean Rowe, US
PO83 Introducing a tailor-made care pathway specific to young women diagnosed and receiving treatment for breast cancer. Elizabeth Vella, MT

No responsibility is assumed by the organisers for any injury and/or damage to persons or propriety as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions or ideas contained in the material herein. Organisers recommend that independent verification of diagnosis, therapies and dosages should be made. Every effort has been made to faithfully reproduce the materials as submitted. However, no responsibility is assumed by the organisers for any omissions or misprints.

Efrat Dagan, University of Haifa, Haifa, IL
Matteo Lambertini, Dana-Farber Cancer Institute, Boston, US
Megan McCann, Young Survival Coalition, New York, US





Participants were invited to submit an abstract on breast cancer in young women, in one of the following categories:

• Basic/Translational Research;
• Clinical Research;
• Advocacy and Nursing

The acknowledgement of receipt of the abstract will immediately follow the submission. The outcome will be notified by 25 July to the first author who will be required to register to the Conference (early registration deadline: 3 August).