From bench to bedside: bringing basic research and clinical oncology together

From bench to bedside: bringing basic research and clinical oncology together


Course Leadership
Chairs: Marina Puchinskaya (BY), Anastasios Stathis (CH/GR), Bojana Stefanovska (USA/MK), Lorenza Wyder (CH)
Host Chair: Rafal Dziadziuszko (PL)
ESO Ambassador: Justyna Bochenek-Cibor (PL)

Course Overview
Advances in cancer research increasingly depend on effective collaboration between basic science and clinical oncology. Yet differences in language, methodology, and priorities often create gaps between the laboratory and the clinic. This course is designed to help bridge that gap by fostering a shared understanding of how discoveries move from experimental models to patient care and back again.

The course is aimed at basic and translational researchers looking to better understand how research is designed, implemented, and evaluated in the clinical setting, as well as clinicians working in oncology who wish to deepen their knowledge of preclinical and translational research and its role in drug development and clinical trials.

Through a structured programme combining lectures, keynote sessions, hands on discussions, and laboratory visits, participants will explore key topics across the research continuum from target selection, experimental models, and biomarker development to early  and late phase clinical trials, companion diagnostics, and statistical considerations. 
By bringing together experts from basic science, pathology, molecular diagnostics, biostatistics, and clinical oncology, this course provides a unique platform for interdisciplinary dialogue, learning, and networking. Participants will gain valuable insights into how different disciplines contribute to successful cancer research and will be better equipped to collaborate across the bench to bedside spectrum
VENUE
The course will be held at Medical University of Gdansk, Poland

LANGUAGE
The course will be held in English. No translation will be provided.

REGISTRATION FEE
Selected participants will be required to confirm their attendance by paying a registration fee of EUR 225,00. 
The fee includes:
  • Access to the full course and its educational resources
  • Up to 3 nights’ accommodation at event hotel (arrival: Thursday 15 April – departure: Saturday 17 or Sunday 18 April 2027)
  • Meals as outlined in the programme
Travel costs are not covered and must be arranged independently.

ESO College members at the time of application and local participants who don’t require accommodation will receive a 50% discount on the registration fee. 

The fee is a non-refundable contribution towards organisational costs and will not be reimbursed in the case of withdrawal or non-attendance, regardless of the reason. 

ACCREDITATION
A certificate of attendance will be issued upon completion of:
  • 100% attendance at the in-person course
  • Completion of the evaluation questionnaire and self-learning test
An application to the European Accreditation Council for Continuing Medical Education (EACCME) will be submitted to obtain CME credits.

ESO COLLEGE MEMBERSHIP
Participation in this course grants eligibility to join the ESO College and allows existing members to earn 12 ESO College credits toward their progression.
Visit ESO College dedicated section for more information on membership and benefits. 

INSURANCE
Participants are advised to take out personal and travel insurance. ESO is not responsible for incidents during the event. 

CONTACTS
Corinne Hall – chall@eso.net
Dolores Knupfer – dknupfer@eso.net
15/04/2027 18:00

Arrivals & Registration

16/04/2027 08:30

Welcome and Introduction

Rafal Dziadziuszko (PL) Marina Puchinskaya (BY) Anastasios Stathis (CH) Bojana Stefanovska (US) Lorenza Wyder (CH)

16/04/2027 08:50

ESO, the College and what ESO has done for me

Justyna Bochenek-cibor (PL)

16/04/2027 09:00

Session 1: Targets and models

09:00

Target selection and validation, drug types and characteristics

09:40

Cellular models in cancer: how to choose them, 2D vs 3D, genetic manipulation, functional assays

Francesco Bertoni (CH)
10:20

Mouse models for oncology: from xenografts and synegeic models to GEMMs to fully humanized mice


16/04/2027 11:00

Coffee break


16/04/2027 11:30

Session 2: Biomarkers, molecular and histopathology

11:30

Genomic Characterization, NGS and Advanced Molecular Technologies

Antonio Marra (IT)
12:10

Pathology in oncology: IHC, AI-assisted diagnostics and spatial proteomics

Paolo Nuciforo (ES)

16/04/2027 12:50

Lunch


16/04/2027 13:50

Liquid vs. tissue biopsies: techniques, challenges and opportunities

Christian Rolfo (US)

16/04/2027 14:30

Keynote 1: From bench to bedside: The success story of Parp Inhibitors

Ruth Plummer (UK)

16/04/2027 15:30

Coffee break


16/04/2027 16:00

Lab visits (rotation)

Pathology lab - Molecular lab - Phase I unit

16/04/2027 20:00

Group dinner

17/04/2027 09:00

Session 3: From lab to patients: Biomarkers and Phase I trials

09:00

Different types and aspects of biomarkers in clinical trials

Christophe Le Tourneau (FR)
09:00

Phase I trials

Anastasios Stathis (CH)

17/04/2027 10:00

Session 4: Later phases trials: Phase II-III trials and statistics

10:00

Phase II and III trials

10:30

Statistical considerations in clinical trials

Christina Yap (UK)

17/04/2027 11:00

Coffee break


17/04/2027 11:30

Session 5: Hands-on informaton on writing and runing a clinical trial

11:30

How to write and plan general concept of a trial protocol

12:00

How to run a drug development research group

12:30

Clinical Research in Poland

Rafal Dziadziuszko (PL)
12:45

Overview of EACR

13:00

Roundtable: Dos and Don'ts in clinical trials


17/04/2027 13:15

Lunch


17/04/2027 14:15

Pre-clinical research proposals

Bojana Stefanovska (US) Lorenza Wyder (CH)

17/04/2027 15:00

Clinical research proposals

Marina Puchinskaya (BY) Anastasios Stathis (CH)

17/04/2027 15:45

Coffee break


17/04/2027 16:15

Keynot lecture 2: The importance and success of companion diagnostics

Jan Trøst Jørgensen (DK)

17/04/2027 17:00

Closing remarks


17/04/2027 19:30

Faculty Dinner (participants free evening or departures)

Anastasios Stathis profile photo
Anastasios Stathis

Oncology Institute Of Southern Switzerland, Eoc, Clinic Of Hematology, Bellinzona, CH

Antonio Marra profile photo
Antonio Marra

European Institute of Oncology IRCSS, Early Drug Development for Innovative Therapies, Milan, IT

Bojana Stefanovska profile photo
Bojana Stefanovska

Howard Hughes Medical Institute, University of Texas Health San Antonio, San Antonio, Texas, USA

Christian Rolfo profile photo
Christian Rolfo

The Arthur G. James Comprehensive Cancer Center, Division of Medical Oncology, Columbus, OH, US

Christina Yap profile photo
Christina Yap

The Institute of Cancer Research, Clinical Trials and Statistics Unit (ICR-CTSU), London, UK

Christophe Le Tourneau profile photo
Christophe Le Tourneau

Gustave Roussy, Early phase clinical trials & Head and Neck oncology, Villejuif, FR

Francesco Bertoni profile photo
Francesco Bertoni

Ior Institute Of Oncology Research, Lymphoma & Genomics Research Program, Bellinzona, CH

Jan Trøst Jørgensen profile photo
Jan Trøst Jørgensen

Dx-Rx Institute, Fredensborg, DK

Justyna Bochenek-cibor profile photo
Justyna Bochenek-cibor

St' Lukas Hospital, Radiation Therapy Dept., Tarnów, PL

Lorenza Wyder profile photo
Lorenza Wyder

Oncology Drug Discovery consultant, Zurich, CH

Marina Puchinskaya profile photo
Marina Puchinskaya

"kravira" Medical Centre, Surgical Dept., Minsk, BY

Paolo Nuciforo profile photo
Paolo Nuciforo

Vall d'Hebron Institute of Oncology (VHIO), Molecular Oncology Group, Barcelona, ES

Rafal Dziadziuszko profile photo
Rafal Dziadziuszko

Medical University of Gdansk, Oncology and Radiotherapy Dpt., Gdansk, PL

Ruth Plummer profile photo
Ruth Plummer

Newcastle University Centre for Cancer, Translational and Clinical Research Institute, Newcastle upon Tyne, UK

Application Deadline: 11 January 2027

PARTICIPATION
The course is limited to 50 participants (25 clinicians and 25 researchers), selected through a competitive application.

Ideal candidate: 
  • Researchers working in basic research
  • Researchers working in translational research
  • Clinicians working in oncology with an interest in preclinical, translational and clinical research.
  • At least 2 years of experience in oncology (research or clinical)
  • Fluency in English
  • Reside within ESO’s geographical reach: Europe, Mediterranean countries, or Latin America 
HOW TO APPLY
If interested, please apply online. 
The application process involves completing an online questionnaire, where you will provide details about: 
  • Your work experience and training
  • Your research experience and publications
  • Your motivation and personal commitment to participating in this activity
During the application, you will also need to upload the following documents in PDF format: 

Applicants are invited to submit a proposal or project of general interest (template above) outlining either a research project they are currently involved in or a research idea that may be exploratory or theoretical in nature, aimed at stimulating discussion in light of modern research strategies and future perspectives. Proposals do not need to be immediately feasible or ready for practical implementation.

Selected participants will have the opportunity to present and discuss their research project in the format of a slide presentation (max. 5 -10 min) to the participants and faculty members during the course (as mentioned in the programme). Please include up to 3 precise questions you would like to discuss with the group.

SELECTION PROCESS

Applications are evaluated through a two-step process:

Automated Scoring: Some responses are assessed using a predefined scoring system to ensure fairness and consistency. Points are assigned based on your answers.

Committee Evaluation: Other sections, including your qualitative responses, are reviewed and scored by our selection committee.

This type of evaluation ensures a transparent and unbiased selection of top candidates for participation in this activity.
Before you start completing the online application form, please be sure you have all the requested files (CV, Recommendation letter, and Research proposal) ready to be uploaded to the system. Online applications will not be considered unless all the files are uploaded. 

Selected participants will be notified by end of January 2027

You will be asked to accept ESO’s Data Protection Statement during the application process.